Hand Eczema Not Improving? Causes, Triggers & When to Seek Help
Hand eczema can be more than dry skin. Discover why some cases don’t respond to moisturisers, what triggers flare-ups, and how to manage symptoms effectively.
Author: Dr. Sreedhar Krishna
Date: 26.02.2026
Hand Eczema Not Improving? Causes, Triggers & When to Seek Help
Hand eczema can be more than dry skin. Discover why some cases don’t respond to moisturisers, what triggers flare-ups, and how to manage symptoms effectively.
Why your hand eczema might not be responding to creams
Hand eczema can be incredibly frustrating, especially when creams and moisturisers seem to do nothing. Recent research has shed light on why some cases are so stubborn: chronic eczema on the hand isn’t just dry skin” or a simple rash. Scientists have found that it shares immune system features with both eczema (atopic dermatitis) and psoriasis. This means the inflammation is more complex than previously thought, which is why some people see limited improvement with standard treatments.
Understanding the causes
The mixed immune signature in hand eczema means that your skin’s defences are overactive in multiple ways. Factors like frequent hand washing, irritants from cleaning products, and environmental allergens can all exacerbate flare-ups. Genetics can also play a role, making some individuals more prone to persistent inflammation.
Managing hand eczema day-to-day
- Moisturise frequently: Use thick, fragrance-free creams or ointments after washing your hands throughout the day. Look for ingredients like ceramides or glycerin to help restore your skin barrier.
- Avoid irritants: Wear gloves whenever possible to protect your hands from harsh soaps, detergents, and chemicals.
- Reduce scratching: Try cold compresses or gentle tapping instead of scratching to soothe itching without damaging the skin.
- Be aware of triggers: Stress, certain foods, and seasonal changes can worsen eczema, so monitor patterns and adapt routines where possible.
When to seek help
If flare-ups persist despite consistent care, a dermatologist can provide guidance tailored to your skin type and severity. Chronic hand eczema may require more targeted approaches, and professional advice can help prevent complications such as infections or thickened skin.
Key Takeaway
Hand eczema is more than dry skin; understanding the biology behind it can help you manage flare-ups more effectively and reduce frustration.
Dr Sreedhar Krishna is a UK-based Consultant Dermatologist with a specialist clinical focus on acne, including the safe prescribing and monitoring of isotretinoin and other systemic acne treatments. He is the Chief Medical Officer and co-founder of skindoc, a consultant-led dermatology service providing both in-person and online care. His work centres on evidence-based acne management, patient safety, and maintaining high clinical standards in UK digital dermatology.
